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PRODUCTS BY APPLICATION

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sales@marshall-tufflex.com www.marshall-tufflex.com

| 37

Bio trunking has demonstrated effectiveness against:

Methicillin resistant Staphylococcus aureus (MRSA): an antibiotic resistant,

opportunist pathogen that can survive on surfaces within the hospital

environment.

Klebsiella pneumoniae: an opportunist pathogen affecting people with

a weakened immune system.

Streptococcus pyogenes: tonsillitis, scarlet fever, necrotising fasciitis

(the ‘flesh-eating bug’).

Vancomycin-resistant Enterococcus faecalis: E.faecalis: a concern when antibiotic

resistance is acquired.

Escherichia coli: All of us are colonised by E.coli in our gut but this bacterium

can cause infections if it is transferred to a wound or a different part of the body

causing severe food-associated illness.

Pseudomonas aeruginosa: a common bacterium found in water and other

environments and is associated with burns infections, medical device infections

and food spoilage.

Acinetobacter baumanii: is associated with HAI and is often resistant to antibiotics.

Bacillus subtilis is a spore forming bacterium with the ability to form resistant

spores that cause a problem for cleaning and disinfection.

Salmonella: the Salmonella species cause food-borne illness.

Legionella: Legionellosis is a severe form of pneumonia caused by inhalation of

infected aerosols, for example via air conditioning systems.

Lactobacilli are essentially non-pathogenic: they are often used as probiotics.

Some species cause spoilage, for example in the brewing industry.

Corynebacterium pseudodiphtheriticum:, associated with respiratory infection.

The treated curved profile (Sample 2) showed excellent control of both MRSA and Klebsiella Pneumoniae with a greater than 99.9% reduction in bacteria

compared to the untreated flat profile (Sample 1). The bacteria grew on the untreated sample.

White Paper

Joanna Verran is Professor of Microbiology

in the School of Biology, Chemistry and

Health Science at Manchester Metropolitan

University. Her research is interdisciplinary,

involving collaboration with materials

scientists, polymer and dental technologists

and surface engineers focusing on

the interactions occurring between

microorganisms and inert surfaces. In 2008,

Professor Verran wrote a 6-page White Paper

on the effectiveness of silver ion pregnated

antimicrobial trunking for Marshall-Tufflex.

Here are a few extracts from that paper:

“In the hospital environment, patients are

particularly susceptible to infection, thus

reduction in the transfer of microorganisms

directly from person to person and indirectly

via inanimate objects, is a key objective. The

microorganisms present may also be more

resistant to antibiotics.

“… ‘silver ions’ …. exert a bactericidal effect

at very low concentrations. Unlike antibiotics,

which have specific targets present in microbial

cells thus demonstrating ‘selective toxicity’ …

silver, like other biocides, is toxic to multiple

components of bacterial cell metabolism.

These include damage to the bacterial cell wall

and membrane permeability.

“… damage leads to blockage of transport and

enzyme systems, alterations of proteins, …

and binding of microbial nucleic acid, which

prevents protein synthesis and cell division.

“… rapid or sustained release is important …

demonstrated by impregnated surfaces where

the silver is mobile and essentially renewable

to the surface. Coatings might, in contrast, be

lost or exhausted more rapidly.”

To download the White Paper in full, please

go to

www.marshall-tufflex.com

TEST RESULTS:

Marshall-Tufflex Report 2709051

LABORATORY:

Thomson Research Associates Inc., Ontario, Canada

TEST ORGANISM:

Methicillin Resistant Staphylococcus Aureus (MRSA)

Quantitative Assessment of Activity – ISO 22196:2007

MRSA

Concentration of starting inoculum

4.94 x 10

5

CFU/mL

Sample Description

Number of

Log Value

R = [log(B/C)]

% Survival

bacteria recovered

Test Results

1.

Flat profile – Blue Tape, White PVC –

7.19 x 10

6

6.9

------

------

untreated control

2.

Curved profile – Red Tape, White PVC –

<2.00 x 10

1

<1.3

>5.6

<0.1%

Treated with Ultra-Fresh CA-16

Trunking for laboratory and healthcare environments